Aiming at planning of the optimal airspace of the stand off jammer in support penetration operations, the range of the jammer and the detection range of the radar after jamming are determined, the concepts of the standoff active jamming strategy, the route safety interval and the effective jamming segment are introduced and the calculation formulas are given. The evaluation function is constructed based on three parameters the effective jamming segment, the number of jammers and the distance of the jammer from the radar center. The model of the standoff active jamming airspace planning is established. The model is characterized, and the grey wolf optimization algorithm is used to solve it. In order to reduce the probability of falling into local optimum of the algorithm when solving the model, the nonlinear adjustment parameters and the memory function are utilized to improve the grey wolf optimization algorithm, and then the corresponding optimal airspace is planned. Simulations are carried out to verify the rationality of the model and the effectiveness of the algorithm, and the airspaces under different decision preferences are achieved.